Current and New Studies

These studies are proposed to begin or are already enrolling subjects in the Western Pennsylvania area.  Follow the links to find out more.

Pragmatic Airway Resuscitation Trial (PART) (PROPOSED STUDY)

This research trial studies patients in cardiac arrest.  Cardiac arrest is a medical emergency where the heart stops beating, the patient collapses suddenly, and the patient stops breathing normally. Typically, paramedics are called to the...


Established Status Epilepticus Treatment Trial (ESETT) (PROPOSED STUDY)

Status  Epilepticus  (SE)  is  a  life-­‐threatening  condition  in  which  the  brain  is  in  a  state  of  persistent  seizure.  SE  is  ...


Study of Tranexamic Acid during Air Medical Prehospital transport (STAAMP) trial

Although advances in the care of the severely injured patient have occurred over the last decade, the most acute threat to severely injured patients is uncontrolled hemorrhage (bleeding). This bleeding results in significant early death and the...


Amiodarone, Lidocaine or Placebo (ALPS) - Enrollment Complete

ENROLLMENT IS COMPLETE!  This study has completed enrollment and data analysis is beginning.  Thanks to all members of the community and to the paramedics who conducted this trial!  Results are expected to be known around April 2016...


Prehospital Air Medical Plasma (PAMPer) trial

Although advances in the care of the severely injured patient have occurred over the last decade, the most acute threat to severely injured patients is uncontrolled hemorrhage (bleeding).  This bleeding results in significant early death and...


Hypotensive Resuscitation for Hemorrhagic Shock after Trauma

How Much Intravenous Fluid should be Administered to Trauma Patients? When patients suffer severe trauma (injury), they may have internal or external bleeding.  One consequence of bleeding is that there is less blood available to carry oxygen...


Emergency Preservation and Resuscitation for Cardiac Arrest from Trauma (EPR-CAT)

Trauma patients who suffer a cardiac arrest have a <10% chance of survival, even if their injuries are technically repairable.  Dr. Peter Safar and Colonel Ron Bellamy proposed over 20 years ago that rapid induction of hypothermia could “buy...


Continuous Chest Compressions (Enrollment Completed)

This randomized clinical trial will test if one method for performing CPR is better than the other for patients with cardiac arrest.  Cardiac arrest is a condition where the heart stops beating, and which leads to death unless treated...