About

Acute Care Research tests promising new treatments for unexpected and sudden life-threatening situations. 

The obligation to improve standard treatments that yield poor results in life-threatening conditions is considered an ethical imperative.


Current Studies

BOOST-3 (Proposed Study)

BOOST3 is a randomized clinical trial (NCT03754114) to compare the effectiveness of two strategies for monitoring and treating patients with TBI in the intensive care unit (ICU).  Traumatic brain injury (TBI) is a major cause of death and...


PPOWER (Pragmatic, Prehospital, Group O Whole Blood Early Resuscitation Trial) - PROPOSED STUDY

Despite advances in the care of patient who suffer life-threatening injuries, few early interventions are available that reduce death and disability from bleeding and shock. Time is critical in the treatment of severe bleeding, but patients may...


News & Events

July 29, 2014

News in Pittsburgh about Exception from Informed Consent Trials

Adam Smeltz, writing for Trib Total Media, has reviewed the STAAMP trial and the PAMPER trial.  Both of these trials use Exception from Informed Consent.  In his article, Smeltz interviews several ethicists who discuss the basis for...


July 15, 2014

Blog Post about Exception from Informed Consent

Jessica Craig writes in the Pitt News about research involving Exception from Informed Consent.  Focussing on the Emergency Preservation and Resuscitation trial, she raises important questions to discuss about the balance between subject...