About

Acute Care Research tests promising new treatments for unexpected and sudden life-threatening situations. 

The obligation to improve standard treatments that yield poor results in life-threatening conditions is considered an ethical imperative.


Current Studies

Study of Tranexamic Acid during Air Medical Prehospital transport (STAAMP) trial

Although advances in the care of the severely injured patient have occurred over the last decade, the most acute threat to severely injured patients is uncontrolled hemorrhage (bleeding). This bleeding results in significant early death and the...


Amiodarone, Lidocaine or Placebo (ALPS)

Pittsburgh is planning to participate in the Amiodarone, Lidocaine, Placebo Study (ALPS).  You can comment on whether this trial should be conducted in this region in our survey.  ALPS is being conducted by the Resuscitation Outcomes...


News & Events

May 1, 2013

Updated Guidance on Exception from Informed Consent for IRBs, Clinical Investigators, and Sponsors

The Food and Drug Administration and the US Department of Health and Human Services released an updated Guidance for Institutional Review Boards, Clinical Investigators and Sponsors on Exception from Informed Consent Requirements for Emergency...


July 8, 2013

Why persons choose to opt out of a trial using exception from informed consent

A study from the Portland site of the Resuscitation Outcomes Consortium interviewed individuals who "opted out" of a study on cardiac arrest treatments.  A total of 46 of 50 persons responded.  The most common reasons were opposition to...